A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK

Inclusion Criteria:

• Active, treatment-naïve choroidal neovascularization (CNV) secondary to AMD,including subfoveal, juxtafoveal, and extrafoveal lesions, or retinal angiomatousproliferations (RAP) lesions with a CNV component that affects the central subfield,as evidenced by FA or OCT in the Study Eye at Screening

• BCVA ETDRS score between 78 and 25 letters (Snellen equivalent ~20/32 and 20/320)inclusive, in the Study Eye at screening and reconfirmed at Day 1.

• Capable of giving signed informed consent.

Exclusion Criteria:

• BCVA of hand motion or worse in the non-Study Eye or non-physical presence of anon-Study Eye (i.e., monocular)

• Fibrosis or atrophy of >50% of the lesion size and/or involving the foveal center ofthe Study Eye at Screening