Harm Reduction for Smokers With Mental Illness

Last updated: October 15, 2024
Sponsor: Dartmouth-Hitchcock Medical Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Tobacco Use Disorder

Treatment

SWITCH IT

E-cig Provision Only

Clinical Study ID

NCT06543407
02002328
R01DA057729-01A1
R01DA057729
  • Ages > 21
  • All Genders

Study Summary

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT

Eligibility Criteria

Inclusion

Diagnostic Criteria (must have one to be eligible):

  • Schizophrenia

  • Bipolar disorder

  • Major Depressive Disorders

  • Posttraumatic disorder

  • Other anxiety disorders

Additional Inclusion Criteria:

  • 21 years or older;

  • English-speaking;

  • Daily smoker (at least 10 cigarettes/day);

  • At least one quit attempt in the past 5 years using evidence- based pharmacotherapyor behavioral cessation support;

  • Not currently interested in quitting.

Exclusion

Exclusion Criteria:

  • Currently residing in a nursing home;

  • Current diagnosis of Asthma;

  • Cognitive impairment (score <26 on the Telephone Interview for Cognitive Status (TICS);

  • Current use of e-cigarettes (>once a week);

  • Psychiatric instability (hospitalized in the past month);

  • Current AND moderate to severe substance use disorder;

  • Pregnant or planning to become pregnant;

  • Use of any smoked products other than cigarettes;

  • Current unstable medical illness making e-cigarette unsafe (e.g., recent heartattack, cancer);

  • Participation in SWITCH IT pilot study.

Study Design

Total Participants: 250
Treatment Group(s): 2
Primary Treatment: SWITCH IT
Phase:
Study Start date:
October 01, 2024
Estimated Completion Date:
March 31, 2028

Connect with a study center

  • Seven Counties Services

    Louisville, Kentucky 40203
    United States

    Active - Recruiting

  • Homer Stryker MD School of Medicine (WMed)

    Kalamazoo, Michigan 49008
    United States

    Site Not Available

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