Pediatric sepsis is a serious clinical syndrome leading to organ dysfunction develops in
children due to infection. Various scoring systems are used to diagnose, treat and asses
for pediatric sepsis. The most common of these Pediatric Risk of Mortality Score III
(PRISM III) and Pediatric Logistic Organ Dysfunction (PELOD) scores. PRISM III is a set
of 17 physiologic scores measured within the first 24 hours of ICU admission that
predicts mortality risk based on the variable. In addition PELOD measures morbidity by
assessing dysfunction in six organ systems. These scores are important in the management
of pediatric sepsis.
tools, but they also have some limitations. For example, the PRISM III score, does not
take into the reason for the admission, underlying disease, infectious agent and response
to treatment of the patient. PELOD score does not reflect the duration and severity of
organ dysfunction. Therefore, new studies and improvements in the definition of pediatric
sepsis and scores are in progress. Pediatric SOFA (pSOFA) score is another option for
definition and to approach the pediatric sepsis. It is used to assess the severity of
sepsis and organ function in children. These criteria include respiratory,
cardiovascular, hepatic, coagulation, renal and neurological systems. For each system,
specific parameters are considered and scored. These scores are summed to calculate the
SOFA score and the risk of organ failure is estimated. The Pediatric Functional Status
Scale (FSS) is a rapid, objective and reliable tool used to assess the functional status
of children during hospitalization. FSS, mental status, sensory function, communication,
motor function, nutrition and respiratory status and each area is given a score between 1
(normal) and 5 (very severe dysfunction). Total scores range from 6 to 30. In recent
years, a new set of criteria called the Phoenix criteria a definition of pediatric sepsis
has been proposed. Phoenix criterias which includes both systemic inflammatory response
syndrome (SIRS) and organ dysfunction criterias aims more accurate and early recognition
of pediatric sepsis. Whether the Phoenix criteria are compatible with PRISM III and PELOD
scores has not yet been investigated. The aim of this study to understand the
compatibility of Phoenix Score, International 2005 SIRS criterias and PRISM III, PELOD
scoring systems. Defining pediatric sepsis in our research, epidemiology, scoring systems
and prognosis. In addition, we will evaluate the advantages and disadvantages of the
Phoenix criteria and assess the compatibility in pediatric sepsis scoring systems. The
subject of our research is the use of the Phoenix criteria for pediatric sepsis. The aim
of this study was to evaluate whether the 2005 SIRS - Sepsis diagnostic and grading
criteria, pSOFA, PRISM III and PELOD scores are compatible and to compare their
prognostic predictive power. The study is a 1-year prospective observational study.
Patients will not undergo any interventional procedure or blood tests due to this study.
No intervention will be made in the treatment protocol.
In this study, Akdeniz University medical patients admitted to the Faculty of Pediatric
Emergency Department with clinical sepsis suspicion will be included in the study. In
2024 it was aimed to evaluate whether the Phoenix criteria, which are recommended to be
used to evaluate the prognosis of sepsis in pediatric patients, are compatible with the
2005 SIRS sepsis diagnosis and grading criteria, pSOFA, PRISM III and PELOD scores, which
were widely used for this purpose in previous years and described in detail in the
introduction section, and to compare their predictive power in terms of morbidity and
mortality.
Patient/Volunteer/Participant definition and number: The patient group consisted of
patients admitted to the Pediatric Emergency Department of Akdeniz University Faculty of
Medicine who were clinically suspected of sepsis or admitted to the general pediatric
service or pediatric intensive care unit with suspected sepsis. The study is a one-year
prospective observational study. The number of patients will be determined by the number
of patients admitted during this period and the group of patients with suspected sepsis.
