AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS

Last updated: March 18, 2026
Sponsor: Powerful Medical
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Angina

Chest Pain

Circulation Disorders

Treatment

N/A

Clinical Study ID

NCT06528821
AI-ECG-TIMI_v1
  • Ages 18-85
  • All Genders

Study Summary

AI ECG TIMI is an investigator-initiated, international, and multicenter registry of acute coronary syndrome patients aimed to identify electrocardiographic findings detected by an AI model predicting coronary blood flow alteration. The aim of the study is to identify electrocardiographic findings detected by an automated artificial intelligence (AI) model that can predict coronary blood flow alteration as assessed by the TIMI grade flow at the very moment of the invasive coronary angiography in patients with acute coronary syndromes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with acute coronary syndromes undergoing invasive coronary angiography asclinically indicated.

  • Availability of a standard 12-lead ECG performed at invasive coronary angiogrambefore percutaneous coronary intervention (maximum within 15 min before vascularaccess).

  • Age ≥18 years.

Exclusion

Exclusion Criteria:

  • Individuals presenting for a non-emergent (elective) cardiac catheterization.

  • Individuals presenting with chronic coronary syndrome (CCS) or stable anginasymptoms.

  • Individuals without symptoms suspicious for acute coronary syndromes.

  • Individuals with contraindications for cardiac catheterization.

Study Design

Total Participants: 800
Study Start date:
December 10, 2024
Estimated Completion Date:
May 16, 2026

Connect with a study center

  • LKH Hochsteiermark, Standort Bruck

    Bruck an der Mur,
    Austria

    Site Not Available

  • LKH II Standort West

    Graz, 8020
    Austria

    Site Not Available

  • Medical University of Graz

    Graz,
    Austria

    Site Not Available

  • OLV Aalst

    Aalst,
    Belgium

    Site Not Available

  • AZ Sint Jan

    Bruges,
    Belgium

    Site Not Available

  • AZ Sint Jan

    Brugge,
    Belgium

    Site Not Available

  • Jessa Ziekenhuis

    Hasselt,
    Belgium

    Site Not Available

  • University Hospital D'Annunzio Chieti

    Chieti,
    Italy

    Site Not Available

  • San Pietro Hospital

    Rome,
    Italy

    Site Not Available

  • Sant´Andrea Hospital

    Rome,
    Italy

    Site Not Available

  • Powerful Medical

    Bratislava,
    Slovakia

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.