Low-Dose Ketamine Infusion During Burn Wound Care

Last updated: December 9, 2024
Sponsor: University of Tennessee
Overall Status: Active - Recruiting

Phase

4

Condition

Pain

Skin Wounds

Mood Disorders

Treatment

Ketamine

0.9% NaCl

Clinical Study ID

NCT06506565
23-09751-FB
  • Ages > 18
  • All Genders

Study Summary

The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Admitted to burn service with thermal injury

Exclusion

Exclusion Criteria:

  • unable/unwilling to consent within 72 hours

  • unable to report NRS

  • known contraindication to ketamine

  • < than 18 years of age

  • pregnant

  • incarcerated

  • TBSA over 50 %

Study Design

Total Participants: 140
Treatment Group(s): 2
Primary Treatment: Ketamine
Phase: 4
Study Start date:
July 08, 2024
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • Regional One Health

    Memphis, Tennessee 38103
    United States

    Active - Recruiting

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