Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT

Last updated: January 9, 2025
Sponsor: Krishnadevaraya College of Dental Sciences & Hospital
Overall Status: Active - Recruiting

Phase

1

Condition

Periodontitis

Treatment

Bromelain gel

SRP

chlorhexidine gel

Clinical Study ID

NCT06505759
02-D012-147453
  • Ages 30-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient with have chronic periodontitis in the age group between 30-50 years.

  • Patients having ≥20 teeth.

-.Patients with radiographic evidence of bone loss in atleast two teeth.

  • Patients who are systematically healthy.

  • Patients with localized pockets with probing depth of ≤ 5mm.

  • Patients who are cooperative and able to attend the hospital for regular follow-up.

Exclusion

Exclusion Criteria:

  • Patients who have received any surgical or nonsurgical therapy during past 6months

  • Pregnant or lactating females.

  • Use of systemic antibiotics in the past 6 months.

  • Patient who are not willing to give a written informed consent

Study Design

Total Participants: 36
Treatment Group(s): 3
Primary Treatment: Bromelain gel
Phase: 1
Study Start date:
July 01, 2024
Estimated Completion Date:
July 31, 2025

Study Description

36 sites with periodontal pocket depth measuring 4-6mm were selected. The sites selected were divided into

  1. Group I (Control)- 12 sites with Probing depth of ≥5mm treated with scaling and root planing alone.

  2. Group II -12 sites with Probing depth of ≥5mm treated with scaling and root planing followed by placement of bromelain gel.

  3. Group III -12 sites with Probing depth of ≥5mm treated with scaling and root planing followed by placement of chlorhexidine gel.

periodontal pack was placed and patient was recalled at 1week,4th week and 12th week

Connect with a study center

  • Dr. NALLAGATLA VAMSI VENKATA KRISHNA SAI

    Bengaluru, Karnataka 562157
    India

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.