Phase
Condition
Retina
Myopic Macular Degeneration
Macular Degeneration
Treatment
ACDN-01
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Key Inclusion Criteria:
Presence of mutations in the ABCA4 gene
ABCA4 retinopathy phenotype (Stargardt disease type 1 or cone-rod dystrophy)
Area of atrophy located in the macula of the study eye
BCVA of 20/80 (0.6 logMAR) or worse
Exclusion
Key Exclusion Criteria:
The presence of pathogenic or likely pathogenic mutations in other genes known tocause cone-rod dystrophy or Stargardt maculopathy
Retinal disease other than ABCA4-related retinopathy
Presence of a medical condition (systemic or ophthalmic), psychiatric condition,including substance abuse disorder, or physical examination or laboratory findingthat may in the opinion of the principal investigator and sponsor preclude adherenceto the scheduled study visits, safe participation in the study, or affect theresults of the study.
Study Design
Study Description
Connect with a study center
University of San Francisco
San Francisco, California 94158
United StatesSite Not Available
Vitreo Retinal Associates
Gainesville, Florida 32607
United StatesActive - Recruiting
Bascom Palmer Eye Institute
Miami, Florida 33136
United StatesActive - Recruiting
Wilmer Eye Institute at John Hopkins
Baltimore, Maryland 21218
United StatesActive - Recruiting
Massachusetts Eye and Ear
Boston, Massachusetts 02114
United StatesActive - Recruiting
University of Michigan Kellogg Eye Center
Ann Arbor, Michigan 48105
United StatesActive - Recruiting
Cincinnati Eye Institute
Cincinnati, Ohio 45245
United StatesActive - Recruiting
Casey Eye Institute OHSU
Portland, Oregon 97239
United StatesActive - Recruiting
Retina Foundation of the Southwest
Dallas, Texas 75382
United StatesActive - Recruiting
Retina Consultants of Texas
Houston, Texas 77401
United StatesActive - Recruiting
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