ECA-enhanced Document Explanation RCT

Last updated: September 29, 2025
Sponsor: Northeastern University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Embodied Conversational Agent (ECA)

Clinical Study ID

NCT06435819
427441
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The investigators will evaluate a computer-animated character that explains medical illustrations to people, comparing the character to having people understand the illustrations on their own, and also comparing the computer character on a computer display to one in immersive virtual reality. The investigators will determine which method leads to the best understanding and lowest anxiety.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Over 18 years old

  • Speaks English or Spanish fluently

  • Is able to independently consent

  • Has adequate corrected vision to read patient education documents

Exclusion

Exclusion Criteria:

  • None

Study Design

Total Participants: 300
Treatment Group(s): 1
Primary Treatment: Embodied Conversational Agent (ECA)
Phase:
Study Start date:
September 05, 2025
Estimated Completion Date:
September 01, 2027

Study Description

The investigators are developing a new approach to explaining patient education documents and illustrations to patients with varying levels of health literacy, involving the use of Embodied Conversational Agents (ECAs). The investigators will evaluate our ECA-augmented Document Explanation tool to determine whether it improves patient learning relative to traditional static patient education documents. The investigators will conduct a 3-arm randomized between-subjects experiment, in which participants read a patient education document with embedded medical illustration, either unaided (CONTROL), with the assistance of an ECA rendered in 2D on a standard computer monitor (ECA-2D), or with the assistance of an ECA in immersive Virtual Reality (ECA-3D).

Connect with a study center

  • Northeastern University

    Boston, Massachusetts 02115
    United States

    Site Not Available

  • Tufts Medical Center

    Boston, Massachusetts 02111
    United States

    Site Not Available

  • Northeastern University

    Boston 4930956, Massachusetts 6254926 02115
    United States

    Active - Recruiting

  • Tufts Medical Center

    Boston 4930956, Massachusetts 6254926 02111
    United States

    Site Not Available

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