Deeper Intubation Make Effects on Cervical Esophageal ESD

Last updated: May 14, 2024
Sponsor: Fujian Provincial Hospital
Overall Status: Active - Recruiting

Phase

4

Condition

Genitourinary Cancer

Precancerous Condition

Treatment

Deeper endotracheal intubation

Clinical Study ID

NCT06420258
K2023-10-008
  • Ages 18-80
  • All Genders

Study Summary

To compare the efficacy and safety of intratracheal deep intubation with traditional intubation in endoscopic submucosal dissection for early esophageal cancer in the cervical esophagus, and to follow up and assess their short-term clinical outcomes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. The lesions mainly involve superficial esophageal squamous cell carcinoma orhigh-grade intraepithelial neoplasia (HGIN) in the cervical esophagus;

  2. There is no evidence of regional lymph node or distant metastasis on endoscopicultrasound (EUS) or CT/MRI imaging;

  3. Participants have a thorough understanding of this study and voluntarily sign theinformed consent form.

Exclusion

Exclusion Criteria:

  1. Patients who have received radiotherapy or chemotherapy before endoscopicsubmucosal dissection surgery; 2. Patients with severe comorbidities who arenot suitable for endoscopic submucosal dissection surgery.

Study Design

Total Participants: 40
Treatment Group(s): 1
Primary Treatment: Deeper endotracheal intubation
Phase: 4
Study Start date:
October 01, 2022
Estimated Completion Date:
December 31, 2026

Study Description

Forty patients with early esophageal cancer in the cervical esophagus scheduled for endoscopic submucosal dissection will be included. They will be randomly divided into two groups using sealed envelopes: approximately 20 patients in the intratracheal deep intubation group and 20 patients in the traditional intubation group. By comparing the operation time, perioperative complications, postoperative short-term complications, and other outcomes, we aim to elucidate the effectiveness and safety of deep intubation in endoscopic submucosal dissection for early esophageal cancer in the cervical esophagus.

Connect with a study center

  • Fujian Provintial Hospital

    Fuzhou, Fujian
    China

    Active - Recruiting

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