Phase
Condition
Diabetes Prevention
Diabetes And Hypertension
Treatment
Placebo Control
N-trans-caffeoyltyramine (NCT) and N-trans-feruloyltyramine (NFT)
Clinical Study ID
Ages 18-50 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Fasting Blood Glucose between 100-125 mg/dL;
and BMI range 25-30 kg/m2;
and waist circumference ≥80cm for women and ≥90cm for men;
Exclusion
Exclusion Criteria:
Weight loss or gain ≥4.5 kg within 90 days of visit 1.
Use of weight loss medications within 90 days of visit 1.
History of gastrointestinal surgery (e.g., bariatric surgery) or cosmetic procedures (e.g., liposuction) for weight/fat reducing purposes.
Use of dietary supplements or related products that, in the judgment of theInvestigator, are likely to markedly affect weight loss or appetite within 30 daysof visit 1.
History of extreme dietary habits (e.g., Atkins diet, etc.), as judged by theInvestigator.
History of an eating disorder (e.g., anorexia nervosa, bulimia nervosa, or bingeeating) diagnosed by a health professional.
Current medical diagnosis of type 1 or type 2 diabetes mellitus.
HbA1c ≥48 mmol/mol (6.5%) as measured at visit 1.
History of a chronic gastrointestinal disorder, such as peptic ulcer disease ormalabsorption syndrome (mild lactose intolerance or gastroesophageal reflux diseasesare acceptable).
Signs or symptoms of an active infection of clinical relevance within 5 days ofvisit 1. The visit may be rescheduled such that all signs and symptoms have resolved (at the discretion of the Clinical Investigator) at least 5 days prior to visit 1.
Is pregnant, planning to be pregnant during the study period, lactating, or is ofchildbearing potential and is unwilling to commit to the use of a medically approvedform of contraception throughout the study period. The method of contraception mustbe recorded in the source document.
Any condition the Investigator believes would interfere with his or her ability toprovide informed consent, comply with the study protocol, or which might confoundthe interpretation of the study results or put the person at undue risk.
Excessive alcohol consumption (> 2 Drinks, 60 ml of Whisky Per Day).
Study Design
Connect with a study center
Diabetes Foundation (India)
New Delhi, 110 016
IndiaActive - Recruiting
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