Phase
Condition
Opioid Use Disorder
Pain
Chronic Pain
Treatment
Patient-Oriented Dosing (POD)
Standard Buprenorphine Dosing Condition
Pain Self-Management (PSM)
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
Adults at least 18 years old
Patient at a participating clinic
Ability to speak, read, and understand English
Capable of providing informed consent
Access to phone and/or internet
Documented diagnosis of Opioid Use Disorder (OUD)
On a stable dose of an oral or sublingual buprenorphine mono or combination product (<4 times per day, daily dosage <32 mg) for at least 7 days during incident newepisode of care
Have high impact chronic pain (Grade 3), based on the Graded Chronic PainScale-Revised (GCPS-R)
Exclusion
Exclusion Criteria:
An individual who meets any of the following criteria will be excluded from participation in this study:
Under 18 years of age
Have cancer-related pain
Are currently in jail, prison, or overnight facility as required by court of law orhave pending legal action that could prevent participation in study activities
Currently prescribed 32mg of an oral or sublingual buprenorphine mono or combinationproduct
Currently prescribed an injectable formulation of buprenorphine
Pregnancy or intention to become pregnant within 4 months of enrollment
Currently prescribed naltrexone or received naltrexone (Vivitrol) injection in thepast 60 days
History of hypersensitivity to buprenorphine that a clinician-determined causedserious rash/hives/pruritus, bronchospasm, angioneurotic edema, or anaphylacticshock
Currently prescribed/taking methadone or have taken methadone in the past 30 days
Had an intentional suicide attempt within the past 3 months
Individuals with common comorbidities, such as depression, anxiety, or alcohol, methamphetamine, and other substance use disorders will not be excluded.
Study Design
Connect with a study center
Alcohol and Drug Abuse Program (ADAP) - UM Addiction Treatment Center
Baltimore, Maryland 21223
United StatesSite Not Available
Comprehensive Care Practice (CCP) - Johns Hopkins Bayview Medical Center
Baltimore, Maryland 21224
United StatesSite Not Available
Outpatient Addiction Treatment Services (OATS)
Baltimore, Maryland 21201
United StatesActive - Recruiting
MATClinics
Dundalk, Maryland 21222
United StatesSite Not Available
Wells House
Hagerstown, Maryland 21740
United StatesSite Not Available
Alcohol and Drug Abuse Program (ADAP) - UM Addiction Treatment Center
Baltimore 4347778, Maryland 4361885 21223
United StatesSite Not Available
MATClinics
Dundalk 4353765, Maryland 4361885 21222
United StatesSite Not Available
Wells House
Hagerstown 4357141, Maryland 4361885 21740
United StatesSite Not Available
Central City Concern (CCC)
Portland, Oregon 97209
United StatesSite Not Available
OHSU Harm Reduction Bridges to Care (HRBR)
Portland, Oregon 97239
United StatesSite Not Available
OHSU Internal Medicine Clinic (IMC)
Portland, Oregon 97239
United StatesSite Not Available
Recovery Works Northwest (RWNW)
Portland, Oregon 97233
United StatesSite Not Available
Central City Concern (CCC)
Portland 5746545, Oregon 5744337 97209
United StatesSite Not Available
OHSU Harm Reduction Bridges to Care (HRBR)
Portland 5746545, Oregon 5744337 97239
United StatesSite Not Available
OHSU Internal Medicine Clinic (IMC)
Portland 5746545, Oregon 5744337 97239
United StatesSite Not Available
Recovery Works Northwest (RWNW)
Portland 5746545, Oregon 5744337 97233
United StatesSite Not Available
UPMC Latterman Family Health Center
McKeesport, Pennsylvania 15132
United StatesSite Not Available
UPMC St. Margaret Family Health Center
New Kensington, Pennsylvania 15068
United StatesSite Not Available
UPMC Internal Medicine Recovery Engagement Program (IM-REP)
Pittsburgh, Pennsylvania 15219
United StatesSite Not Available
UPMC Magee-Womens Pregnancy and Women's Recovery Center (PWRC)
Pittsburgh, Pennsylvania 15213
United StatesSite Not Available
UPMC Latterman Family Health Center
McKeesport 5200499, Pennsylvania 6254927 15132
United StatesSite Not Available
UPMC St. Margaret Family Health Center
New Kensington 5203211, Pennsylvania 6254927 15068
United StatesSite Not Available
UPMC Internal Medicine Recovery Engagement Program (IM-REP)
Pittsburgh 5206379, Pennsylvania 6254927 15219
United StatesSite Not Available
UPMC Magee-Womens Pregnancy and Women's Recovery Center (PWRC)
Pittsburgh 5206379, Pennsylvania 6254927 15213
United StatesSite Not Available
WVU Crisis Support & Recovery Center
Martinsburg, West Virginia 25401
United StatesSite Not Available
WVU Chestnut Ridge Comprehensive Addiction Treatment Program (COAT)
Morgantown, West Virginia 26505
United StatesSite Not Available
WVU Crisis Support & Recovery Center
Martinsburg 4813878, West Virginia 4826850 25401
United StatesSite Not Available
WVU Chestnut Ridge Comprehensive Addiction Treatment Program (COAT)
Morgantown 4815352, West Virginia 4826850 26505
United StatesSite Not Available

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