Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial

Last updated: March 10, 2024
Sponsor: Le Yu
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anesthesia

Treatment

Drug: ciprofol injection

Clinical Study ID

NCT06312345
2024.3.10-2024.5.1
  • Ages 55-75
  • All Genders

Study Summary

Ciprofol, a novel intravenous general anesthetic with a chemical structure akin to propofol, boasts significantly enhanced potency. It offers a rapid onset, reduced incidence of injection pain, and minor impact on the cardiovascular system. However, clinical research regarding ciprofol's use for anesthesia induction in cardiac surgery remains limited.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Elective surgery patients
  2. Aged 55 to 75
  3. New York Heart Association class II or III cardiac functions
  4. Median sternotomy approach for coronary artery bypass grafting or heart valvereplacement procedures

Exclusion

Exclusion Criteria:

  1. With a history of benzodiazepine allergy
  2. Significant liver or kidney insufficiency
  3. Coagulation dysfunction
  4. Neurological or psychiatric disorders
  5. Undergone major surgery within the past three months.

Study Design

Total Participants: 80
Treatment Group(s): 1
Primary Treatment: Drug: ciprofol injection
Phase:
Study Start date:
March 11, 2024
Estimated Completion Date:
May 10, 2024

Connect with a study center

  • Shanghai East Hospital of Tongji University

    Shanghai, Shanghai 200120
    China

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.