Toric Intraocular Lens Implantation in Pediatric Cataract

Last updated: March 16, 2026
Sponsor: Kazakh Eye Research Institute
Overall Status: Completed

Phase

N/A

Condition

Vision Loss

Eye Disease

Astigmatism

Treatment

Non-Toric IOLs

congenital/pediatric cataract surgery

Toric IOLs

Clinical Study ID

NCT06294795
02-2024
  • Ages 6-18
  • All Genders

Study Summary

To evaluate the visual and refractive outcomes after an intraocular lens (IOL) implantation in pediatric eyes with cataract and preexisting corneal astigmatism

Eligibility Criteria

Inclusion

Inclusion criteria:

  1. Visually significant cataract;

  2. Corneal astigmatism more than 1.25 diopters;

  3. Children aged ≥ 6 years and < 18 years.

Exclusion

Exclusion criteria:

  1. Patients with a corneal diameter less than 9 mm;

  2. Presence of corneal scarring;

  3. Irregular astigmatism;

  4. Intraocular pressure more than 25 mm Hg;

  5. Active inflammatory process of the eyeball or signs of a previous episode ofinflammation;

  6. Traumatic, subluxated, or complicated cataract;

  7. Persistent Fetal Vasculature;

  8. Diseases of the optic nerve or macula that may limit visual potential;

  9. History of previous intraocular surgeries;

  10. Performing posterior capsulorhexis intraoperatively.

Study Design

Total Participants: 40
Treatment Group(s): 3
Primary Treatment: Non-Toric IOLs
Phase:
Study Start date:
March 01, 2024
Estimated Completion Date:
March 16, 2026

Study Description

This single-center, single-blinded, prospective, randomized controlled trial was performed at two sites of Kazakh Eye Research Institute.

Children with pediatric cataract and corneal astigmatism were included and randomized to two groups for pediatric cataract surgery with toric and non-toric intraocular lens (IOL) implantation. The uncorrected and corrected distance visual acuity, near visual acuity, keratometry data, and residual astigmatism were evaluated.

The purpose of this study is to evaluate the visual and refractive outcomes after a toric IOL implantation in pediatric eyes with cataract and preexisting corneal astigmatism.

Connect with a study center

  • Kazakh Eye Research Institute

    Almaty, 050012
    Kazakhstan

    Site Not Available

  • Kazakh Eye Research Institute

    Almaty 1526384, 050012
    Kazakhstan

    Site Not Available

  • Kazakh Eye Research Institute

    Astana, 010000
    Kazakhstan

    Site Not Available

  • Kazakh Eye Research Institute

    Astana 1526273, 010000
    Kazakhstan

    Site Not Available

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