Adjunctive Mindfulness During Opioid Tapering for patientS With Chronic Pain (The AMOS Study)

Phase

N/A

Condition

Chronic Pain

Pain

Treatment

Mindfulness-Oriented Recovery Enhancement: (MORE) group

Psychoeducation

Clinical Study ID

NCT06268522

2023P001582

Ages > 18
All Genders

Study Summary

This study is a Randomized Controlled Trial exploring the effects of a Mindfulness interventions in reducing pain interference and opioid dose in patients with Chronic Low Back Pain. A total of 200 opioid-using patients with chronic pain, male and female participants will be enrolled, with a need for 160 completers. Patient will be randomly assigned into the Mindfulness-Oriented Recovery Enhancement or the Psychoeducation comparison control group.

Eligibility Criteria

Inclusion

Inclusion criteria:

age>18yo
Chronic Low Back Pain as seen on medical history as well as score of >3 on painvisual analog scale (VAS) at the start of experimental sessions.
receiving prescription opioids for three or more months and planning to starttapering their opioids with their provider.
willing to be randomized to one of the two behavioral treatment. Patients referredor self-referred to the study from an outside clinic will also be able toparticipate (we will be in contact with their prescribing provider)
able and willing to perform/tolerate pain procedures (e.g., QST)
able to communicate fluently in English
able to use a smartphone or laptop for the virtual therapy program

Exclusion

Exclusion criteria:

Current illicit substance use (e.g marijuana use will be exempted) at screening orduring trial as verified by urine toxicology screen and/or self-report for allparticipants;
Medical condition known to influence QST or participation in the MORE intervention;serious psychiatric condition;
regular meditation practice
cognitive impairment
pregnancy
lack of English fluency
severe OUD
inability to provide informed consent.

Study Design