Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias

Last updated: May 6, 2024
Sponsor: Université du Québec à Chicoutimi
Overall Status: Active - Recruiting

Phase

N/A

Condition

Sjögren-larsson Syndrome

Mental Disability

Limb Spasticity

Treatment

IMPACT - rehabIlitation prograM for sPAstiC aTaxias

Clinical Study ID

NCT06261424
2024-1426
  • Ages > 16
  • All Genders

Study Summary

Spastic ataxias are a group of diseases causing symptoms such as walking difficulties and balance impairments that lead to a high risk of falls. No pharmacological treatments exist to treat these diseases. Unfortunately, little effort is made to develop non-pharmacological treatments specific to spastic ataxias despite the detrimental impact of the disease on several aspects of an individual's life and the high cost of falls for society each year. The three objectives of this project are: 1) to determine the effect of a 12-week rehabilitation program on disease severity as compared with usual care for individuals with spastic ataxias; 2) to identify which factors can help (or not) the implementation of the program in the clinical settings ("reel world"); and 3) to explore the cost-benefits of IMPACT [rehabIlitation prograM for sPAstiC aTaxias]. The team has developed the program to specifically target symptoms present in these patients and was previously pilot-tested. Based on the results obtained in this pilot project, positive effects are expected concerning the disease severity of participants. The investigators want, with this project, provide to health care professionals an option to offer better-suited services to people living with spastic ataxia worldwide.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • have a confirmed genetic diagnosis of ARSACS or SPG7
  • be able to maintain standing position and to transfert
  • be authorized by their treating neurologist
  • speak French or English
  • be able to give informed consent.

Exclusion

Exclusion Criteria:

  • have active participation in a rehabilitation program (self-reported information)
  • have another condition causing physical limitations
  • be uncomfortable in a swimming pool
  • be pregnant.

Study Design

Total Participants: 84
Treatment Group(s): 1
Primary Treatment: IMPACT - rehabIlitation prograM for sPAstiC aTaxias
Phase:
Study Start date:
February 01, 2024
Estimated Completion Date:
March 31, 2027

Connect with a study center

  • CIUSSS de la Capitale-Nationale, Hôpital de Baie-Saint-Paul

    Baie-Saint-Paul, Quebec G3Z 0K3
    Canada

    Site Not Available

  • CIUSSS de la Capitale-Nationale, Hôpital de La Malbaie

    La Malbaie, Quebec G5A 1T1
    Canada

    Site Not Available

  • CIUSSS du Centre-Sud-de-l'Île-de-Montréal, installation Centre de réadaptation Lucie-Bruneau

    Montréal, Quebec H2H 2N8
    Canada

    Active - Recruiting

  • CIUSSS de la Capitale-Nationale, installation IRDPQ

    Québec, Quebec G1M 2S8
    Canada

    Active - Recruiting

  • Clinique des maladies neuromusculaires du Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean, installation Hôpital Jonquière

    Saguenay, Quebec G7X 7X2
    Canada

    Active - Recruiting

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