Phase
Condition
Allergy (Peanut)
Allergies & Asthma
Allergy
Treatment
Avoidance
Consumption
Clinical Study ID
Ages 18-40 Female Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
• o Subject must be able to understand and provide informed consent.
English-speaking adults, 18 years or older. (Spanish speaking adults may be includedafter consent document is translated and Spanish speaking study representatives areavailable to conduct and answer questions during informed consent process and forstudy follow up.)
Maternal consent must be provided for infants.
Pregnant women from the time pregnancy is confirmed until 27 weeks of gestation.
Self-reported at time of enrollment:
no chronic inflammatory conditions that require long-term systemicimmunosuppressive medications in first or second trimester
carrying a fetus with a first-degree relative (i.e., mother, father, fullsibling) with any self-reported or physician-diagnosed allergic disease (asthma, allergic rhinitis, atopic dermatitis, or food allergy).
Intend to give their infant their own breast milk for more than 3 months.
Can confidently say they have eaten PN and egg and have tolerated consumption withno food allergy reactions.
Willing to be randomized to consumption or avoidance diet.
Uncomplicated pregnancy (no gestational diabetes, no preeclampsia, no hyperemesisgravidarum), self-reported at time of enrollment.
Exclusion
Exclusion Criteria:
Inability or unwillingness of subject to give written informed consent or complywith study protocol.
Known history of renal/liver/cardiac insufficiency in the mother or infant.
Pregnant women with PN or egg allergy.
Pregnant women who refuse to eat PN (or peanut products) and/or eggs.
Physician diagnosed immunodeficiency in the mother or infant.
Current, diagnosed, mental illness or current, diagnosed, or self-reported, drug oralcohol abuse that, in the opinion of the investigator, would interfere with thesubject's ability to comply with study requirements.
Past or current medical problems or findings from medical history that are notlisted above, which, in the opinion of the investigator, may pose additional risksto the mother or infant from participation in the study, may interfere with thesubject's ability to comply with study requirements or that may impact the qualityor interpretation of the data obtained from the study.
Study Design
Study Description
Connect with a study center
University of Rochester
Rochester, New York 14642
United StatesActive - Recruiting

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