Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center

Last updated: February 9, 2026
Sponsor: Baylor Research Institute
Overall Status: Active - Recruiting

Phase

N/A

Condition

Post-traumatic Stress Disorders

Treatment

Treatment as Usual

Brief Prolonged Exposure Therapy

Clinical Study ID

NCT06210711
024-127
  • Ages 18-75
  • All Genders

Study Summary

The purpose of this research is to determine if a brief treatment method is effective for preventing posttraumatic stress disorder (PTSD) and a number of other concerns following injury.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Between the ages of 18 and 75 years old.

  • Admitted to Baylor University Medical Center at Dallas (BUMC), Baylor Scott & WhiteMedical Center at Temple (BSWMC), or Froedtert Hospital and the Medical College ofWisconsin (FH/MCW) Level 1 Trauma Center

Exclusion

Exclusion Criteria:

  • Patients in police custody

  • Patients not fluent in English

  • Patients with severe cognitive impairment

  • Patients who are acutely suicidal

  • Patients with active psychosis

Study Design

Total Participants: 300
Treatment Group(s): 2
Primary Treatment: Treatment as Usual
Phase:
Study Start date:
February 28, 2024
Estimated Completion Date:
September 30, 2027

Study Description

This is a prospective randomized controlled trial examining the efficacy of brief Prolonged Exposure Therapy (Brief PE) delivered to individuals admitted to a Level I Trauma Center to reduce PTSD symptoms. The overall goal of this project is to test a Brief PE (three 60-minute sessions) to reduce psychological distress after injury and to mitigate long-term post-injury distress including PTSD as well as secondary health outcomes (including depression, general anxiety, pain, and quality of life) at 1, 3, and 6 months from baseline. The intervention group (Brief PE) will be compared to standard clinical care with treatment as usual (TAU).

Connect with a study center

  • Baylor University Medical Center

    Dallas, Texas 75246
    United States

    Site Not Available

  • Baylor Scott & White Medical Center - Temple

    Temple, Texas 76508
    United States

    Site Not Available

  • Baylor University Medical Center

    Dallas 4684888, Texas 4736286 75246
    United States

    Active - Recruiting

  • Baylor Scott & White Medical Center - Temple

    Temple 4735966, Texas 4736286 76508
    United States

    Active - Recruiting

  • Froedtert & Medical College of Wisconsin

    Milwaukee, Wisconsin 53226
    United States

    Site Not Available

  • Froedtert & Medical College of Wisconsin

    Milwaukee 5263045, Wisconsin 5279468 53226
    United States

    Active - Recruiting

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