Feasibility Trial Using an Inpatient Insulin Dosing Calculator

Last updated: May 9, 2024
Sponsor: University of Washington
Overall Status: Active - Recruiting

Phase

N/A

Condition

Diabetes And Hypertension

Diabetes Prevention

Diabetes Mellitus, Type 2

Treatment

Initial insulin dosing using the calculator

Clinical Study ID

NCT06206525
STUDY00018906
2T32DK007247-41
  • Ages > 18
  • All Genders

Study Summary

The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission. The main questions it aims to answer are:

  • Whether using this calculator leads to no excessive hypoglycemia?

  • Whether using this calculator leads to a decrease of hyperglycemia?

Participants will receive initial insulin doses by the calculator on hospital admission, and the rest of care will follow standard of care. Participants will be compared with patients in the UW observational cohort who received initial insulin doses by standard of care.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients who are admitted to University of Washington Medical Centers

  • With history of type 2 and/or steroid-induced diabetes mellitus

  • Receiving insulin therapy prior to admission

Exclusion

Exclusion Criteria:

  • Patients who are admitted to ICU or obstetrics ward

  • Patients who are admitted for elective surgery or procedure

  • Patients who present with diabetic ketone acidosis, hyperosmolar hyperglycemic stateor require intravenous insulin infusion

  • Patients who have no meal intake for 24 hours prior to admission, or planned nothingper oral (NPO) during the first 24 hours after admission

  • Patients who report low appetite (25% or less) on admission or have a significantlydecreased level of consciousness that they unlikely eat right after admission

  • Patients who receive enteral feeding after admission

Study Design

Total Participants: 85
Treatment Group(s): 1
Primary Treatment: Initial insulin dosing using the calculator
Phase:
Study Start date:
March 22, 2024
Estimated Completion Date:
February 28, 2025

Connect with a study center

  • Harborview Medical Center

    Seattle, Washington 98104
    United States

    Active - Recruiting

  • UW Medical Center - Montlake

    Seattle, Washington 98195
    United States

    Active - Recruiting

  • UW Medical Center - Northwest

    Seattle, Washington 98133
    United States

    Active - Recruiting

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