Cardiovascular Patients With no Standard Modifiable Risk Factors

Last updated: February 23, 2025
Sponsor: Jordan Collaborating Cardiology Group
Overall Status: Completed

Phase

N/A

Condition

Vascular Diseases

Atherosclerosis

Treatment

Evaluation of risk factors by direct interview with subjects who have atherosclerotic cardiovascular patients

Clinical Study ID

NCT06199869
CVA2024.SMuRFless1
  • Ages > 18
  • All Genders

Study Summary

A growing number of patients develop atherosclerotic cardiovascular disease (ASCVD) despite the absence of standard modifiable risk factors (SMuRF-less). There is scarcity of studies that address this issue in the Middle Eastern population.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • A diagnosis of atherosclerotic cardiovascular disease (ASCVD).

  • Ability to fill the clinical form that evaluates the presence or absence ofcardiovascular risk factors including the 4 SMuRFs.

Exclusion

Exclusion Criteria:

  • Atherosclerotic cardiovascular disease diagnosed before the age of 18 years.

  • Inability to give detailed history of prespecified risk factors.

Study Design

Total Participants: 5540
Treatment Group(s): 1
Primary Treatment: Evaluation of risk factors by direct interview with subjects who have atherosclerotic cardiovascular patients
Phase:
Study Start date:
January 22, 2024
Estimated Completion Date:
January 31, 2025

Study Description

Atherosclerotic coronary artery disease (ASCAD) claims millions of lives annually on a global level and is the leading cause of death in the Middle East. There are four standard modifiable cardiovascular risk factors (SMuRFs): hypertension, type 2 diabetes mellitus, dyslipidemia, and smoking. These are very common in the Middle East and are crucial to be screened for and addressed in an affective manner.

However, an increasing proportion of patients with ASCVD have none of these individual factors (SMuRF-less). Globally, this proportion comprises 11.6% of individuals with stable coronary disease and heart attack. No prior study has addressed the issue of the prevalence of SMuRF-less patients among the whole population of individuals with ASCVD in the Middle East.

Connect with a study center

  • Istishari Hospital

    Amman, 11184
    Jordan

    Site Not Available

  • Yarmouk University School of Medicine

    Irbid,
    Jordan

    Site Not Available

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