A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

Last updated: February 12, 2025
Sponsor: Memorial Sloan Kettering Cancer Center
Overall Status: Active - Recruiting

Phase

3

Condition

Breast Cancer

Carcinoma

Cancer/tumors

Treatment

Volumetric arm measurements

Compression garment use

Range of motion exercises

Clinical Study ID

NCT06144164
23-303
  • Ages 18-75
  • Female

Study Summary

The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Female sex

  • Diagnosis of breast cancer

  • Ages 18 to 75 years

  • Consented for unilateral ALND or for unilateral SLNB with possible ALND

Exclusion

Exclusion Criteria:

  • Male sex

  • Does not speak English

  • Does not fit into study garment

  • Axillary recurrence

  • History of ALND

  • Requirement of bilateral ALND for the treatment of breast cancer

  • Treatment with SLNB only

  • Known anaphylactic allergy to ICG dye used in ILR

  • Impaired decision-making capacity

Study Design

Total Participants: 285
Treatment Group(s): 5
Primary Treatment: Volumetric arm measurements
Phase: 3
Study Start date:
November 16, 2023
Estimated Completion Date:
March 16, 2030

Connect with a study center

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey 07920
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey 07748
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey 07645
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Commack (Limited Protocol Activities)

    Commack, New York 11725
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York 10604
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York 10065
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York 11553
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.