Super-Resolution Ultrasound of the Brain in 3D

Inclusion Criteria:

• Patient aged 18 and over

• Hospitalized patient with ischemic stroke in the deep territory of the middlecerebral artery

• Patient with lesion observable on MRI

• Patient included between 24 hours and 7 days after the ischemic stroke

• Patient with a temporal window which allows soundproofing of the polygon of Willisand the middle cerebral artery

• Patient having signed free, informed and written consent

• Patient affiliated to a social security system (excluding AME)

Exclusion Criteria:

• Contralateral middle cerebral artery territory stroke or contralateral middlecerebral artery occlusion

• Patient with contraindication to Doppler ultrasound with contrast (right-left shunt,severe pulmonary arterial hypertension)

• Patient with hypersensitivity to the active princip of Sonovue (sulfur hexafluoride)or these excipients

• Patient with uncontrolled systemic hypertension

• Patient with respiratory distress syndrome

• Patient under guardianship or curatorship

• Pregnant or breastfeeding patient (positive blood pregnancy test duringhospitalization)

• Patient with damaged skin at the temporal level

• Patient having presented in the 7 days preceding inclusion an acute coronarysyndrome or suffering from unstable ischemic heart disease