CCT-102 or Expectant Management in Delayed Pregnancy Loss

Inclusion Criteria:

1. Age 18 to 50

2. Ability to provide informed consent

3. Hemodynamically stable

4. Closed cervical os

5. If fetus exists, clinical observation indicates gestation is no more than 10 weeks

6. Diagnosis of delayed pregnancy loss, confirmed by ultrasound, based on:

7. Embryonic demise: no embryonic cardiac activity when embryo measures 7 mm orgreater; OR,

8. Anembryonic pregnancy: mean gestational sac diameter of 25 mm or greater, withno detectable embryo.

Exclusion Criteria:

1. Unwillingness or inability to comply with the study protocol and visit schedule

2. Diagnosis of an incomplete or inevitable abortion including more than slightbleeding at enrollment and/or open os within the prior week.

3. Confirmed or suspected ectopic pregnancy or undiagnosed adnexal mass

4. Hemoglobin <10 g/dL

5. Coagulation disorder, inherited porphyrias, and/or current anticoagulants use

6. Chronic adrenal failure

7. Concurrent chronic corticosteroid therapy

8. History of trophoblastic disease

9. Current presence of an IUD

10. History of allergy or contraindications to the use to mifepristone, misoprostol, orother prostaglandins

11. Any condition that, in the opinion of the investigator, makes the patient unsuitablefor study entry

12. Any other current medical condition that jeopardizes the patient's ability to safelyparticipate in the trial