Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation.

Last updated: October 31, 2023
Sponsor: Hospital Nacional Profesor Alejandro Posadas
Overall Status: Active - Recruiting

Phase

N/A

Condition

Inflammation

Hyponatremia

Treatment

hyponatremia

Clinical Study ID

NCT06109532
HINDIP162023
  • All Genders

Study Summary

Prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnosis confirmed by PCR, non structural protein 1 (NS1) antigen or IgM serology. Plasma sodium at admission.

Exclusion

Exclusion Criteria:

  • None

Study Design

Total Participants: 530
Treatment Group(s): 1
Primary Treatment: hyponatremia
Phase:
Study Start date:
January 01, 2016
Estimated Completion Date:
October 31, 2023

Study Description

Background Dengue infection is becoming more prevalent worldwide and is associated with systemic inflammation. Systemic Inflammation is associated with non-osmotic release of ADH.

Methods: Participants conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.

Connect with a study center

  • Ladislao Diaz Ballve

    Haedo, Buenos Aires 1706
    Argentina

    Active - Recruiting

  • Hospital Posadas

    Buenos Aires, 1684
    Argentina

    Active - Recruiting

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