A Clinical Trial to Assess the Safety and PK of OMN6 in HABP or VABP Caused by Acinetobacter Baumannii Complex

Inclusion Criteria:

1. A signed informed consent form.

2. Male or female patients 18 years or older

3. A diagnosis of either a HABP or a VABP

4. ABC infection of the lower respiratory tract suspected based on a positive rapidtesting of respiratory specimens

5. Women of childbearing potential (WOCBP) (i.e., not post-menopausal or surgicallysterilized) must have a negative highly sensitive urine or serum pregnancy testbefore randomization.

6. Acute Physiology and Chronic Health Evaluation II (APACHE II) score between 10 and 24

Exclusion Criteria:

1. Moderate to severe reduction of renal function

2. Liver dysfunction

3. Evidence of septic shock

4. Acute respiratory distress syndrome.

5. Immunosuppressed patients (due to either immunosuppressant drugs or to any medicalcondition).

6. History of any known hypersensitivity to colistin or to carbapenems

7. Any condition or circumstance that, in the opinion of the investigator, wouldcompromise the safety of the patient or the quality of the study data