Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania

Last updated: March 4, 2025
Sponsor: George Washington University
Overall Status: Active - Recruiting

Phase

3

Condition

Anemia

Treatment

Multiple Micronutrient Supplements with 30 mg of elemental iron

Multiple Micronutrient Supplements with 60 mg of elemental iron

Multiple Micronutrient Supplements with 45 mg of elemental iron

Clinical Study ID

NCT06079918
MMS-MAP
  • Ages > 18
  • Female
  • Accepts Healthy Volunteers

Study Summary

This is an individually randomized controlled trial to assess the effect of multiple micronutrient supplements (MMS) containing 60 and 45 mg iron as compared to MMS containing 30 mg of iron (standard UNIMMAP formulation) on maternal moderate or severe anemia. This study will help inform countries like Tanzania that currently use IFA containing 60 mg of iron regarding the dose of iron to use in MMS.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Attending first ANC visit at study clinics

  • Pregnant women < 20 weeks gestation by last menstrual period (LMP)

  • Aged ≥ 18 years old

  • Intending to stay in Dar es Salaam until 6 weeks post delivery

  • Provides informed consent

Exclusion

Exclusion Criteria:

  • Severe anemia (defined as hemoglobin < 8.5 g/dL per Tanzania standard of care)

  • Sickle cell disease (SS and SC) and hemoglobin C disease (CC) as tested byHemoTypeSC

  • Concurrently enrolled in another nutritional clinical trial

  • Pregnant women with disability or condition which would impair their ability toprovide informed consent and complete study procedures.

Study Design

Total Participants: 6381
Treatment Group(s): 3
Primary Treatment: Multiple Micronutrient Supplements with 30 mg of elemental iron
Phase: 3
Study Start date:
March 03, 2025
Estimated Completion Date:
June 30, 2027

Connect with a study center

  • Muhimbili University of Health and Allied Sciences

    Dar es Salaam,
    Tanzania

    Active - Recruiting

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