Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)

Last updated: May 12, 2026
Sponsor: Augusta University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Osteoarthritis

Treatment

Sub Acute Whole Body Vibration Training

Clinical Study ID

NCT06058169
2054289
  • Ages 40-75
  • All Genders

Study Summary

The purpose of this proposal is to understand how the Vibrant Health Ultimate whole-body vibration (WBV) machine affects pain and inflammation in older adults. The investigators' hypothesize that sub-acute (12 weeks) WBV will lead to improvement in the level of knee pain and improve vascular function via a decrease in systemic inflammation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Symptomatic Osteoarthritic knee pain for at least 6 months.

  • Mean and women

  • Ages 40-75 years old

Exclusion

Exclusion Criteria:

  • <40 years old or >75 years old

  • History of balance issues

  • History of falls

  • Epilepsy

  • Pregnancy

  • The use of whole-body vibration in the past 6 months

  • Previous knee surgery within last 3 years

  • Unable to stand for at least 20 minutes (for whole body vibration training)

Study Design

Total Participants: 30
Treatment Group(s): 1
Primary Treatment: Sub Acute Whole Body Vibration Training
Phase:
Study Start date:
April 25, 2025
Estimated Completion Date:
September 01, 2026

Study Description

Knee osteoarthritis (KO) is a leading cause of disability and medical cost. Whole body vibration (WBV) has emerged as an exercise alternative that may be more tolerable than traditional forms of exercise, such as treadmill walking/running or cycling. Similar to traditional exercise, research supports that WBV can be very beneficial for your health. In fact, a single bout of WBV increases circulating concentrations of inflammatory markers. WBV is safe and effective, WBV training has been conducted in obesity, elderly, patients with diabetes, patients with lung disease, as well as patients with knee osteoarthritis.

Connect with a study center

  • Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology

    Augusta, Georgia 30912
    United States

    Active - Recruiting

  • Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology

    Augusta 4180531, Georgia 4197000 30912
    United States

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.