A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

Inclusion Criteria:

• Participant must be aged 18 to 90 years at the time of providing informed consent

• First-ever clinical stroke, defined according to World Health Organization criteriaas rapidly developing clinical signs of focal (at times global) disturbance ofcerebral function lasting more than 24 hours, within the past 4 weeks;

• Confirmed paresis of the arms and/or legs which does not resolve within 1 day,according to the NIHSS score (a score of > 0 on Question 5 or 6 of the scale)between Day 3 and day 14 after the stroke

• Capable of giving informed consent which includes compliance with the requirementsand restrictions listed in the ICF and in this protocol

Exclusion Criteria:

• Upper or lower extremity functional impairment prior to stroke per investigatorjudgement (e.g., modified Rankin Scale >2);

• Presence of significant/major neurological impairment that might affect muscle tone (other than limb paresis);

• Severe multi-impairment or diminished physical condition before stroke that couldhave caused paresis/spasticity/motor deficit per investigator judgement;

• Life expectancy of less than 12 months as a result of severity of stroke or otherillnesses (e.g. cardiac disease, malignancy, etc.)

• Participation in any interventional study