Knee Osteoarthritis, Aging and Metabolic Syndrome

Last updated: March 17, 2024
Sponsor: Sohag University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Knee Injuries

Metabolic Syndrome

Diabetes Prevention

Treatment

xray

Clinical Study ID

NCT05955573
Soh-Med-23-07-17MS
  • Ages > 30
  • All Genders

Study Summary

Osteoarthritis (OA) is the most prevalent form of arthritis. Its pathogenesis remains poorly understood. Though historically regarded as a disease of mechanical degeneration, it is now appreciated that inflammation plays an important role in OA pathogenesis

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients who met the American College of Rheumatology (ACR) clinical criteria for kneeOA and had symptomatic OA of at least 1 knee (index knee), with a Kellgren / Lawrence (K/L) score ≥ 1 in that knee

Exclusion

Exclusion Criteria:

  • Any patient with a history of trauma to the knee
  • Any other form of arthritis (e.g., rheumatoid arthritis, seronegativespondyloarthropathies, gout, pyrophosphate disease, or other crystal arthropathy)

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: xray
Phase:
Study Start date:
August 20, 2023
Estimated Completion Date:
August 31, 2024

Study Description

  1. Place of the study: Sohag university hospital.

  2. Type of study: Cross-Sectional Observational study

  3. Study period: Six months to one year The study will include Patients who met the American College of Rheumatology (ACR) clinical criteria for knee OA .

The following details will be obtained:

  • Demographic data : Age ,Sex ,Marital status ,Occupation ,Residence ,Education level

    ,Anthropometrical measures which included waist circumference (WC) and blood pressure (BP) will be obtained,History of chronic diseases (eg; Diabetes mellites, Hypertension)

  • Clinical information: Symptom and its Duration. Plain radiographs of at least one knee [anteroposterior (A/P), lateral} will be taken.

  • Laboratory findings included fasting blood sugar, serum levels of triglycerides, High-density lipoprotein cholesterol and total cholesterol.

Connect with a study center

  • Sohag Faculty of Medicine

    Sohag,
    Egypt

    Active - Recruiting

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