Multicenter Retrospective Study of Isoflurane in Refractory and Super-Refractory Status Epilepticus

Last updated: September 22, 2025
Sponsor: Hopital of Melun
Overall Status: Completed

Phase

N/A

Condition

Epilepsy (Pediatric)

Epilepsy

Treatment

Isoflurane

Clinical Study ID

NCT05830864
MIR-2023-01
  • Ages > 18
  • All Genders

Study Summary

Isoflurane might be used as anticonvulsive therapy in refractory status epilepticus. The aim of the study is to assess the efficiency of Isoflurane in this indication.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age > 18 years, hospitalized in ICU between 2016-01-01 and 2023-01-01, sufferingrefractory status epilepticus treated by inhaled Isoflurane as third anticonvulsivetherapy

Exclusion

Exclusion Criteria:

  • post-anoxic refractory status epilepticus after cardiac arrest, withdrawal ofconsent for medical data use

Study Design

Total Participants: 66
Treatment Group(s): 1
Primary Treatment: Isoflurane
Phase:
Study Start date:
June 30, 2024
Estimated Completion Date:
September 22, 2025

Study Description

Investigators will collect in 4 ICUs the data from consecutive patients hospitalized between january 2016 and january 2023. Included patient were those treated by Isoflurane for refractory status epilepticus.

Connect with a study center

  • Ch Bethune Beuvry

    Beuvry, 62660
    France

    Site Not Available

  • Ch Bethune Beuvry

    Beuvry 3032903, 62660
    France

    Site Not Available

  • CHU Brest

    Brest, 29200
    France

    Site Not Available

  • CHU Brest

    Brest 3030300, 29200
    France

    Site Not Available

  • GH Sud Ile de France, Hôpital de Melun-Sénart

    Melun, 77000
    France

    Site Not Available

  • GH Sud Ile de France, Hôpital de Melun-Sénart

    Melun 2994651, 77000
    France

    Site Not Available

  • CH Toulon - Sainte Musse

    Toulon, 83000
    France

    Site Not Available

  • CH Toulon - Sainte Musse

    Toulon 2972328, 83000
    France

    Site Not Available

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