Incidence of Severe COVID-19 Infection in Patients With CLL or B-NHL Who Received Pre-exposure Prophylaxis With Tixagevimab and Cilgavimab in Italy.

Last updated: November 22, 2023
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto
Overall Status: Active - Recruiting

Phase

N/A

Condition

Lymphoma, B-cell

Lymphoma

Chronic Lymphocytic Leukemia

Treatment

N/A

Clinical Study ID

NCT05803395
CLL2423
  • Ages > 18
  • All Genders

Study Summary

This is an observational retrospective and prospective multicenter study aimed at describing the role of the COVID -19 prophylaxis with Tixagevimab and Cilgavimab in CLL or indolent B-NHL patients who received first COVID-19 prophylaxis dose between March 2022 and October 2022.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age ≥ 18 years
  2. Patient with CLL or indolent B-NHL who received the first COVID-19 prophylaxis dosewith Tixagevimab and Cilgavimab as per label indication between March 2022 and October
  4. Signed informed consent, if applicable

Exclusion

Exclusion Criteria: None

Study Design

Total Participants: 954
Study Start date:
September 12, 2023
Estimated Completion Date:
September 30, 2024

Study Description

This is an observational retrospective and prospective multicenter study aimed at describing the role of the COVID -19 prophylaxis with Tixagevimab and Cilgavimab in CLL or indolent B-NHL patients.

All CLL or indolent B-cell NHL patients (follicular lymphoma, marginal zone lymphoma, lymphoplasmacytic lymphoma) who received first COVID-19 prophylaxis dose with Tixagevimab and Cilgavimab according to AIFA indication between March 2022 and October 2022 will be included in the study.

Each patient will be followed for a maximum of 12 months from the first COVID-19 prophylaxis dose.

Connect with a study center

  • UOC Ematologia AO Cosenza

    Cosenza,
    Italy

    Active - Recruiting

  • Ematologia AOU S.Anna

    Ferrara,
    Italy

    Active - Recruiting

  • Ematologia AOU Careggi

    Firenze,
    Italy

    Active - Recruiting

  • ASST Lecco Ospedale A.Manzoni

    Lecco,
    Italy

    Active - Recruiting

  • UOC Ematologia ATMO

    Livorno,
    Italy

    Active - Recruiting

  • ASST Grande Ospedale Metropolitano Niguarda

    Milano,
    Italy

    Active - Recruiting

  • SCDU Ematologia

    Novara,
    Italy

    Active - Recruiting

  • Dipartimento Oncologico La Maddalena

    Palermo,
    Italy

    Active - Recruiting

  • UOC DI ONCOEMATOLOGIA AOR Villa Sofia - Cervello

    Palermo,
    Italy

    Active - Recruiting

  • Ematologia Università "Sapienza" Roma

    Roma,
    Italy

    Active - Recruiting

  • IRCCS Istituto Clinico Humanitas

    Rozzano,
    Italy

    Active - Recruiting

  • UOC Ematologia Casa Sollievo della Sofferenza

    San Giovanni Rotondo,
    Italy

    Active - Recruiting

  • SCDU Ematologia e terapie cellulari AO Mauriziano

    Torino,
    Italy

    Active - Recruiting

  • Ematologia Ospedale S.Chiara

    Trento,
    Italy

    Active - Recruiting

  • UOC ematologia ULSS2 Marca Trevigiana

    Treviso,
    Italy

    Active - Recruiting

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