The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors

Last updated: May 6, 2025
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Overall Status: Active - Recruiting

Phase

N/A

Condition

Oral Cavity Cancer

Treatment

ENHANCE Intervention - Exercise and Nutrition

ENHANCE Intervention - Nutrition Only

Clinical Study ID

NCT05798780
MCC-22330
  • Ages > 18
  • All Genders

Study Summary

The purpose of the study is to design a physical activity and dietary intervention for head and neck cancer patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • >18 years old

  • Newly diagnosed tumors of the oral cavity, oropharynx, hypopharynx, or larynx

  • No documented or observable psychiatric or neurological disorders that wouldinterfere with study participation (e.g., dementia, psychosis)

  • Able to speak and read English

  • Able to consume food orally

  • Willing to consume an alternative Mediterranean diet

  • Scheduled to receive treatment with radiation or chemoradiation

  • Screened via the Physical Activity Readiness Questionnaire (PAR-Q+) with medicalclearance of treating physicians, as necessary

  • Able to provide informed consent

Exclusion

Exclusion Criteria:

  • Women who are pregnant

  • Head and Neck Cancer not the primary diagnosis

  • Patients scheduled to receive surgery

  • Patients on enteral or parental nutrition

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: ENHANCE Intervention - Exercise and Nutrition
Phase:
Study Start date:
April 06, 2023
Estimated Completion Date:
June 30, 2026

Connect with a study center

  • Moffitt Cancer Center

    Tampa, Florida 33612
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.