Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)

Last updated: March 17, 2025
Sponsor: University of Miami
Overall Status: Active - Recruiting

Phase

2

Condition

Hormone Deficiencies

Myasthenia Gravis (Chronic Weakness)

Hypertriglyceridemia

Treatment

Strength Training

Ursolic Acid

Clinical Study ID

NCT05776862
20221142
COPBC
  • Ages 18-65
  • All Genders

Study Summary

This study will evaluate if Ursolic Acid supplementation may be effective in reducing muscle loss and improving blood sugar control in the SCI community.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Male and female individuals with paraplegia having chronic (> 1 year) motor-completeand incomplete (AIS A/B/C) injuries from T2-T8

  2. Male and female individuals wi4.th chronic (> 1 year) motor-complete and incomplete (AIS A/B/C) injuries from C4-C7

Exclusion

Exclusion Criteria:

  1. Pregnant or planning to become pregnant

  2. Women who are breastfeeding

Study Design

Total Participants: 20
Treatment Group(s): 2
Primary Treatment: Strength Training
Phase: 2
Study Start date:
March 27, 2023
Estimated Completion Date:
June 01, 2025

Connect with a study center

  • University of Miami - Miami Project to Cure Paralysis

    Miami, Florida 33136
    United States

    Active - Recruiting

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