A Study to Evaluate the Safety, Tolerability and Drug Levels of BMS-986447 in Healthy Participants

Last updated: April 3, 2024
Sponsor: Bristol-Myers Squibb
Overall Status: Completed

Phase

1

Condition

N/A

Treatment

BMS-986447

Placebo

Clinical Study ID

NCT05760937
IM054-003
  • Ages 18-55
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of the study is to evaluate the safety, tolerability and drug levels of single, oral doses of BMS-986447 in healthy participants.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Body mass index between 18 and 30 kilograms per metered square (kg/m^2), inclusive.
  • Healthy male and female participants without clinically significant deviation fromnormal in medical history, physical examination, ECG, and clinical laboratorydeterminations.
  • A negative COVID-19 test, which will be performed in the manner mandated by theclinical side where the study is being conducted, at screening and check-in Day -2.

Exclusion

Exclusion Criteria:

  • Participant has any condition that confounds the ability to interpret data from thestudy.
  • Participant has any condition including the presence of laboratory abnormalities,which places the participant at unacceptable risk if the participant was toparticipate in the study.
  • Any major surgery or planned surgery (except gastrointestinal [GI] surgery, asdescribed below) within 12 weeks of study intervention administration. Note: Other protocol-defined inclusion/exclusion criteria apply.

Study Design

Total Participants: 32
Treatment Group(s): 2
Primary Treatment: BMS-986447
Phase: 1
Study Start date:
March 10, 2023
Estimated Completion Date:
November 27, 2023

Connect with a study center

  • Anaheim Clinical Trials, LLC

    Anaheim, California 92801
    United States

    Active - Recruiting

  • Local Institution - 0001

    Anaheim, California 92801
    United States

    Site Not Available

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