Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.

Last updated: January 31, 2023
Sponsor: University of Baghdad
Overall Status: Active - Recruiting

Phase

1

Condition

Williams Syndrome

Vascular Diseases

Diabetes And Hypertension

Treatment

N/A

Clinical Study ID

NCT05719181
528622
  • Ages 25-70
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Effect of Recombinant Human Bone Morphogenetic Protein-2 with an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients have good oral hygiene.
  • Systemic healthy individuals ,Age more than18 years.
  • Healed edentulous area for at least 6 months after tooth extraction (delayed implantprotocol).
  • Patients have at least two missing teeth in the jaw (canine to 1st molar area)indicated for the dental implant.

Exclusion

Exclusion Criteria:

  • Presence of systemic diseases preventing implantation.
  • Previous implantation or augmentation of the same region.
  • The need for additional bone augmentation procedures (such as maxillary sinusaugmentation)
  • Partial or total edentulous ridge associated with a severe knife-edge ridge .
  • Acute infection or any pathological lesion a the implant site.
  • Allergy to one of the materials to be used during operation.
  • Pregnancy.
  • Radiation therapy, bisphosphonate drugs , Osteoradionecrosis.

Study Design

Total Participants: 32
Study Start date:
December 06, 2021
Estimated Completion Date:
April 20, 2023

Study Description

The Primary outcome will be measuring the effect of rhBMP- 2/ACS in improving the secondary stability of dental implant by using RFA in comparison to control group.

Secondary outcome association of the effect of other factors (ridge dimension, bone density) on dental implant stability.

Connect with a study center

  • University of Baghdad

    Baghdad, Alresafa 10011
    Iraq

    Active - Recruiting

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