Phase
Condition
Diabetic Kidney Disease
Treatment
Placebo group
Probiotic group
Clinical Study ID
Ages 25-80 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Age between 25 and 80 years old
Suffering from type 2 diabetes and stable medication for 3 months
Detection of HbA1c before meals between 7% and 10%
Stage 1-3a diabetic nephropathies (eGFR > 45 mL/min)
Microalbuminuria estimated between 30 to 300 mg/day
Exclusion
Exclusion Criteria:
Patients with Type I Diabetes Mellius
Patients with inflammatory bowel disease, liver disease, liver cirrhosis, systemiclupus erythematosus, malignancy, and high blood pressure.
Patients with hypoglycemic coma, Diabetic ketoacidosis, hyperosmolar non-ketoticdiabetic coma, or diabetes mellitus acute complications.
Acute infection medical history in past 3 month
Fasting blood glucose >13.3 mmol/L
GPT>100U/L (2.5 times than usual situation)
Vulnerable population (Including breeding or pregnant women, prisoner, aboriginal,disabled population)
Smoker or Alcoholic
Taking Antibiotics in past 1 month
Stably taking probiotics supplements in past 1 months (Yogurt or dairy products wereexcluded)
Taking immunosuppressive drug, angiotensin-converting enzyme inhibitors, orangiotensin receptor blockers in past 3 months
Study Design
Study Description
Connect with a study center
Chung Shan Medical University Hospital
Taichung City, 402
TaiwanActive - Recruiting
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