Septorhinoplasty Post-operative Pain Control With SPG Nerve Block

Last updated: May 29, 2024
Sponsor: University of Florida
Overall Status: Active - Recruiting

Phase

4

Condition

Nasal Obstruction

Treatment

Ropivacaine

Dexamethasone

Placebo

Clinical Study ID

NCT05667324
IRB202201279 -A
  • Ages 18-80
  • All Genders

Study Summary

Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery. This randomized, double-blinded, placebo-controlled study will investigate blocks of the pterygopalatine fossa using a suprazygomatic approach during septorhinoplasty surgery. It is the investigator's hypothesis that this technique will result in decreased post-operative pain and opioid use, and the morbidity associated with it.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient presenting for open or endoscopic septorhinoplasty

  • Age 18-80

  • Normal oral food and water intake before surgery

  • ASA physical classification 1-3

Exclusion

Exclusion Criteria:

  • Refusal to consent

  • Patients without a cellular phone or who are unable to accept text messages

  • Allergy to opioid narcotics

  • ASA physical classification of 4 or higher

  • Patient requires other surgery in addition to septorhinoplasty

  • Age > 80 or <18

  • Any underlying chronic pain condition or ongoing opioid use over the preceding 3months

  • Presence of any other factor which, at the discretion of any member of the studyteam, makes the patient a poor candidate for block placement.

  • Presence of any other factor which, at the discretion of any member of the studyteam, makes the patient a poor candidate for research participation.

  • Pregnant women

Study Design

Total Participants: 120
Treatment Group(s): 3
Primary Treatment: Ropivacaine
Phase: 4
Study Start date:
April 12, 2023
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • UF Health of University of Florida

    Gainesville, Florida 32610
    United States

    Active - Recruiting

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