Ability of a Cat Food to Reduce Respiratory Symptoms in Cat Allergic Patients

Last updated: March 3, 2023
Sponsor: MASK-air SAS
Overall Status: Active - Recruiting

Phase

N/A

Condition

Common Cold

Nasal Obstruction

Allergy

Treatment

N/A

Clinical Study ID

NCT05656482
KM00232
  • Ages 18-70
  • All Genders

Study Summary

Cat allergy is the most common animal allergy, affecting approximately 1 in 5 adults worldwide. The prevalence of allergy to furry animals is increasing, and cat allergy is a major risk factor for the development of asthma and rhinitis.

Fel-d1 is the major feline allergen, to which 95% of cat allergic people react. All cats produce Fel-d1 regardless of breed, age, coat type, sex or weight. Fel-d1 is contained primarily in the saliva and sebum of cats.

This allergy manifests itself as allergic rhinitis (AR) (sneezing, cold, coughing, conjunctivitis with watering and itching), severe asthma, and irritation and swelling of the skin when scratched.

A new approach to managing cat allergies is to neutralize the allergens at the source by feeding domestic cats a diet containing anti-Fel-d1 IgY antibodies. The purpose of this pilot study is to determine whether feeding domestic cats a food containing an egg product with anti-Fel d1 IgY (PRO PLAN® LIVECLEAT®) induces a reduction of allergic symptoms in their owners.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Uncontrolled allergic rhinitis (with or without treatment)
  • Persistent allergic rhinitis with worsening of symptoms upon exposure to cats
  • Presence of one or two cats in the household, whose diet consists mainly of dry kibble
  • Agreement of the patient to change the food of the cat(s) and to feed it exclusivelywith the test kibbles during the study.
  • Diagnosis of cat allergy defined by a positive prick test to standardized cat allergenor cat-specific IgE.
  • Absence of allergy to pollens emitted in the region during the 4 months following theinclusion date, confirmed by a negative skin test.
  • Person owning an android and/or IOS smartphone and having the possibility to connectto the internet (via phone subscription or WIFI connection),
  • Person who agrees to install the MASK-air application (medical device) on his personalsmartphone,
  • Person having read and understood the information note and having signed theirparticipation agreement before any specific procedure of the study.

Exclusion

Exclusion Criteria:

  • Person planning to be away from the cat(s) for more than one week/month in the 4months following the inclusion visit
  • Patient who has had a new cat in the home for less than one month
  • Patient in regular contact with other animals to which they are allergic
  • Patient with uncontrolled asthma
  • Patient receiving immunotherapy for cat allergies
  • Patient participating or having participated in an allergic rhinitis study within thelast 30 days or 5 half-lives of study medication
  • Person who has difficulty understanding or reading the information
  • Person declaring to be under guardianship, curatorship or safeguard of justice.

Study Design

Total Participants: 50
Study Start date:
May 06, 2022
Estimated Completion Date:
April 15, 2023

Connect with a study center

  • Cabinet médical Lion de Raspail

    Paris, 75014
    France

    Active - Recruiting

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