Changes in Tactile Perception in People With Segmental Exclusion Syndrome

Last updated: July 2, 2024
Sponsor: Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05650398
IRR-CLP-2022-9
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Segmental exclusion syndrome is characterised by the non-use or under-use of a limb segment, most oftenly reported in the distal part, following an injury, without affecting the central nervous system. This syndrome has an important negative impact on the daily life of affected subjects; however, it remains poorly studied, particularly in terms of pathophysiology, and its management is still not specific. Currently, the main pathophysiological hypothesis is an alteration of the afferences related to a dysfunction of the sensorimotor loop. An hypothesis is that this dysfunction could concern the level of tactile perception and that the damage to the distal light touch receptors could play a role in the pathophysiology. The protocol is based on the performance of tests that explore different aspects of light touch: passive, active, dynamic and static sensitivity.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • No history of upper limb involvement

  • Confirmed diagnosis of segmental exclusion > 3 months after injury (2 items assignedto 400 points)

  • Able to understand simple orders

Exclusion

Exclusion Criteria:

  • Central neurological involvement after the initial or pre-existing injury

  • Truncal nerve damage

  • Presence of psychiatric pathology

  • Communication and/or comprehension disorders

  • Presence of other pathology that may lead to sensory disorders (complicateddiabetes, ductal syndrome, ...)

Study Design

Total Participants: 38
Study Start date:
September 26, 2022
Estimated Completion Date:
September 30, 2025

Connect with a study center

  • Institut Régional de Médecine Physique et de Réadaptation

    Nancy, 54000
    France

    Active - Recruiting

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