The Impact of Comorbid Chronic Pain on Older Adults With Depression in Behavioral Activation

Last updated: April 17, 2023
Sponsor: Teesside University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Depression

Pain

Chronic Pain

Treatment

N/A

Clinical Study ID

NCT05646628
293203
ISRCTN63034289
  • Ages > 65
  • All Genders

Study Summary

This qualitative nested sub-study will aim to explore how chronic pain (as defined as pain lasting for more than 3 months) impacts older adults' depression and treatment in a brief psychological therapy of behavioral activation (BA)

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Previously provided optional consent to participate in a qualitative study as part ofthe BASIL+ trial
  2. Not enrolled or offered to take part in any other qualitative study linked with theBASIL+ trial (i.e, the nested BASIL+ qualitative study or the therapeutic alliancesub-study)
  3. Suffering chronic pain. This will be assumed by individual scores on the (short-from
  1. SF-12 and EuroQoal 5th Edition (EQ-5D) at baseline in the BASIL + trial. Patientswho have responded as "moderate, quite a bit or extremely" on question 8 of the SF-12at baseline and/or responded as having "moderate or extreme pain or discomfort" on theEQ-5D question 4 at baseline will be "assumed" to experiencing some level of pain. Afurther 2 telephone screening questions by the PI of this sub-study (Alexandra Carne)will assess how often patients have pain and how pain limits their life/workactivities in the last 3 months. This will confirm the presence of chronic pain.
  1. Participants will have had either a 'favourable' or 'non' favourable' response totreatment. This is defined as having a change of 0.5 SD on the PHQ-9 from baseline tothe primary outcome point at 3 months.

Exclusion

Exclusion Criteria:

  1. Does not fulfill the inclusion criteria

Study Design

Total Participants: 10
Study Start date:
November 28, 2022
Estimated Completion Date:
March 31, 2024

Study Description

The BASIL + trial (Behavioral Activation in Social Isolation) is a National Institute of Health Research (NIHR) funded and approved trial sponsored by Tees, Esk and Wear Valleys NHS Foundation Trust (TEWV) and led by the University of York in the United Kingdom (UK).

Behavioral Activation (BA) is a type of support that may be beneficial for individuals who suffer from social isolation and/ or depression symptoms. BA assists in the continuation or introduction of activities that are significant to patients. These exercises may be beneficial to both physical and emotional health.

The BASIL+ study aims to find out if BA helps reduce or prevent depression and loneliness in older adults who have ongoing health conditions during isolation in the pandemic due to COVID-19.

Chronic pain affects approximately 50-60% of UK older adults and often coexists with depression. This comorbid indication affects approximately 13% of older adults. The literature on the impact of pain on depression outcomes has been steadily rising. Patients who suffer from depression with comorbid pain report significantly lower benefits, including less relief from depressive symptoms and limits the effectiveness of collaborative care for older adults with depression in the US. The collaborative care focused on antidepressant therapy and problem-solving therapy. Together, these findings suggest that pain may be a potential barrier to depression treatment response. It is unknown, however, how chronic pain impacts depression and the treatment of BA.

This sub-study nested in the BASIL+ trial provides an opportunity to explore how chronic pain impacts depression and the treatment they received

Connect with a study center

  • Teesside University

    Middlesbrough, TS1 3BX
    United Kingdom

    Active - Recruiting

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