Evaluation of the Curative Effect of Ru-Yi-Jin-Huang-Saan

Last updated: March 16, 2025
Sponsor: Changhua Christian Hospital
Overall Status: Active - Recruiting

Phase

2

Condition

N/A

Treatment

Ru Yi Jin Huang Powder

Placebo

Clinical Study ID

NCT05638360
RYJHS
  • Ages 20-80
  • All Genders

Study Summary

The purpose of this study is to assess the efficacy and safety of Ru-Yi-Jin-Huang-Saan for the treatment of Colles' fracture.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. People who are over 20 years old and have no lack of mental ability can understandthe content of the experiment and are willing to participate in it.

  2. Patients with Colles' fracture receive surgical fixation(ORIF).

Exclusion

Exclusion Criteria:

  1. People are unable to cooperate with experiments and fill out questionnaires.

  2. Patients have wounds on the back of their wrists.

  3. Patients are allergic to traditional Chinese medicine for external applications orhave used other traditional Chinese medicine for external applications.

  4. Patients have cancer, stroke, and systemic diseases such as severe anemia, thyroiddisease, uncontrolled diabetes, etc.

  5. Pregnant woman.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Ru Yi Jin Huang Powder
Phase: 2
Study Start date:
May 01, 2023
Estimated Completion Date:
September 30, 2025

Study Description

According to the definition of the World Health Organization, Taiwan officially entered the aged society in 2018. The population over the age of 65 exceeds 14% of the total population. Based on this, it is estimated that we will enter a super-aged society in 2026. Because the older the age, the higher the rate of bone loss, and the higher the risk of osteoporosis, the easier it is to fracture due to falls. The incidence of bone fracture is directly proportional to the aging population. Traditional Chinese Medicine(TCM) interventional fracture treatment has a long history and experience.

Many recent studies show that TCM is benefit to reduce risk of total hip replacement and has a positive influence on the prevention of osteoporotic fracture. In drug mechanism research, some Chinese herbal medicine has been proved to promote bone fracture healing . Although most of these researches have been confirmed in the laboratory, little information is available on true patients. In clinical we observe a lot of topical Chinese medicine been used after fracture, so the purpose of this thesis is to investigate the effective of topical Chinese herbal paste. This study may lead to build the usage of guideline after fracture.

Connect with a study center

  • Changhua Christian Hospital

    Changhua, 50006
    Taiwan

    Active - Recruiting

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