Distal Versus Conventional Transradial Artery Access for Coronary Catheterization in Patients With STEMI

Last updated: May 25, 2024
Sponsor: University Hospital of Patras
Overall Status: Active - Recruiting

Phase

N/A

Condition

Hypercholesterolemia

Blood Clots

Heart Disease

Treatment

Coronary angiography +/- percutaneous coronary intervention

Clinical Study ID

NCT05605288
26150/30.09.22
  • Ages > 18
  • All Genders

Study Summary

Recently, a novel distal transradial, through anatomical snuffbox, approach has been proposed for undertaking percutaneous coronary angiography and interventions. The existing literature has evaluated distal transradial access (dTRA) as a feasible and safe approach, with faster hemostasis, lower rates of periprocedural complications and reduced incidence of radial artery occlusion (RAO). Aim of the present study is to compare dTRA versus conventional TRA access in patients with STEMI undergoing coronary angiography and interventions regarding peri- and post-procedural characteristics.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age > 18 years old

  • Indication: ST-Elevation Myocardial Infraction

Exclusion

Exclusion Criteria:

  • Non-palpable radial artery

  • Previous CABG

  • Anatomical restrictions for forearm approach

  • Hemodynamic instability

  • Previous radial artery catheterization from the same arm during the last 30-days

Study Design

Total Participants: 554
Treatment Group(s): 1
Primary Treatment: Coronary angiography +/- percutaneous coronary intervention
Phase:
Study Start date:
May 23, 2024
Estimated Completion Date:
December 01, 2025

Study Description

Gaining vascular access is the first, mandatory step for undertaking percutaneous coronary angiography and interventions. The recent guidelines, published by European Society of Cardiology (ESC), American College of Cardiology (ACC), American Heart Association (AHA) and Society for Cardiovascular Angiography and Interventions (SCAI), propose TRA as the gold standard for acute coronary syndromes (ACS), chronic coronary syndrome (CCS) percutaneous coronary interventions (PCI). Recently, a novel distal transradial, through anatomical snuffbox, approach has been proposed. The existing literature has evaluated distal transradial access (dTRA) as a feasible and safe approach, with faster hemostasis, lower rates of periprocedural complications and reduced incidence of radial artery occlusion (RAO). Mutual point of all the previous RCTs is that excluded patients suffering from ST-elevation Myocardial Infraction (STEMI). Aim of the present study is to compare dTRA versus conventional TRA access in patients with STEMI undergoing coronary angiography and interventions regarding peri- and post-procedural characteristics.

Connect with a study center

  • Department of Cardiology, Centre Hospitalier Universitaire de Charleroi

    Charleroi,
    Belgium

    Active - Recruiting

  • University Hospital of Patras

    Patras, 26500
    Greece

    Active - Recruiting

  • Department of Cardiology, Geneva University Hospitals, Geneva, Switzerland.

    Geneva,
    Switzerland

    Active - Recruiting

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