Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section

Last updated: December 20, 2022
Sponsor: Zagazig University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Vascular Diseases

Dizzy/fainting Spells

Circulation Disorders

Treatment

N/A

Clinical Study ID

NCT05587153
9293/2-2-2022
  • Ages 18-40
  • Female
  • Accepts Healthy Volunteers

Study Summary

Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section

Eligibility Criteria

Inclusion

Inclusion criteria

  • Parturient acceptance.

  • American Society of Anesthesiologists (ASA) II

  • arturient with be gestational age >36 weeks and <41 weeks.

  • Body mass index (BMI) ≤35kg/m2

  • elective caesarean section delivery

Exclusion criteria

  • preeclampsia

  • eclampsia,

  • gestational diabetes

  • Contraindication to regional anaesthesia as allergy, coagulation abnormalities or infection in site of injection.

Study Design

Total Participants: 80
Study Start date:
July 15, 2022
Estimated Completion Date:
December 30, 2022

Study Description

Hypotension following spinal anaesthesia may cause maternal dizziness, nausea, vomiting and fetal acidosis, administration of prophylactic vasopressor agents in pregnant women may cause undesirable effects on the mother and fetus. Perfusion index is the ratio of a pulsatile to a non-pulsatile fraction of blood volume. The increase of the pulsatile fraction manifested during vasodilatation corresponds to a higher PI. So, the patients with a higher PI have a higher risk for post-spinal hypotension. Elevated sympathetic activity before neuraxial anaesthesia was associated with a higher risk for post-spinal hypotension. The significant variability in haemodynamic after the positional change indicates higher sympathetic activity. The high the rise in autonomic activity, the higher the risk for post-spinal hypotension

AIM OF THE WORK:

Prediction of hypotension after spinal anaesthesia in caesarean section either by perfusion index and positional haemodynamic changes

Grouping:

All the recruited patients will be assessed by perfusion index. and by positional haemodynamic changes

Connect with a study center

  • Faculty of medicine

    Zagazig, 44519
    Egypt

    Active - Recruiting

  • Ramy

    Zagazig,
    Egypt

    Active - Recruiting

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