The Sanderson Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening

Key Inclusion Criteria:

• Age ≥30 years within 30 days of enrollment

• Able and willing to provide blood samples per protocol

• Able to comprehend and willing to sign and date the informed consent and HIPAA

• Authorization documents

• Able and willing to allow existing health data to be utilized for study purposes

Key Exclusion Criteria:

• Any history of solid organ or bone marrow transplantation

• Any physical trauma or surgery requiring inpatient overnight hospitalization in the 30 days preceding enrollment

• Received a blood transfusion in the 30 days preceding enrollment

• A medical condition that, in the opinion of the Investigator, should precludeenrollment in the study

• Known to be pregnant

• Any therapy for cancer, including but not limited to surgery, chemotherapy, biologictherapy, immunotherapy, and/or radiation therapy in the 5 years preceding enrollment

• Participated or currently participating in a clinical research study in which anexperimental medication has been administered during the 30 days precedingenrollment

• Participated or currently participating in another Freenome-sponsored clinical study

• For non-cancer groups: Any previous cancer diagnosis in the 5 years precedingenrollment; OR recurrence of the same primary cancer within any timeframe; ORconcurrent diagnosis of multiple primary cancers within any timeframe

• For the cancer groups: Any previous cancer diagnosis in the 5 years precedingenrollment, apart from the current cancer diagnosis; OR recurrence of the sameprimary cancer within any timeframe; OR concurrent diagnosis of multiple primarycancers within any timeframe