Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals

Last updated: April 13, 2023
Sponsor: Capital Medical University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Thrombosis

Treatment

N/A

Clinical Study ID

NCT05413837
CVSAV-HI
  • Ages 18-35
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding the anatomy and variation of normal venous sinuses is essential to identify the intracranial venous lesions.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age 18 - 35 years old.
  2. Confirmed no intracranial diseases, congenital abnormalities such as intracranialhematoma, tumor, vascular malformation, hydrocephalus, etc.
  3. Voluntarily signed informed consent.

Exclusion

Exclusion Criteria:

  1. Any clinical history, including hypertension, diabetes, coronary heart disease,hematologic and rheumatic immune system diseases,cervical spondylosis, anxiety,depression, insomnia, etc.
  2. Internal jugular venous outflow disturbance : MRV from extracranial to aortic archdemonstrates variation or stenosis of the internal jugular vein, vertebral plexus,brachiocephalic vein, and superior vena cava.
  3. Any history of craniocerebral trauma or surgery that affected the existence andrunning of veins.Unhealthy habits such as smoking, heavy drinking, etc.
  4. Women who are pregnant or in preparation for pregnancy or lactation.
  5. Other conditions that the researchers considered might affect the trial andinappropriate for inclusion.

Study Design

Total Participants: 40
Study Start date:
July 06, 2022
Estimated Completion Date:
August 31, 2023

Study Description

The classification of venous sinus and its variation based on the autopsy of patients can not fully reflect the real anatomy and variation of venous sinus in human, and the targeted research on healthy people is still unknown. The main purpose of this research is to use multimodal magnetic resonance technology to study the variation of venous sinus in Chinese healthy population, to preliminarily improve the anatomical classification of venous sinus in Chinese , to verify the the correlation between venous sinus variation and various non-genetic factors at the same time, as well as establishing reliable quantitative evaluation indicators.

Connect with a study center

  • Xuanwu hospital;Capital Medical University

    Beijin, XI Cheng District 100053
    China

    Active - Recruiting

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