Study of ARO-APOC3 in Adults With Dyslipidemia

Inclusion Criteria:

• Adults who are nonpregnant, nonlactating and do not plan to become pregnant duringthe study

• Able and willing to provide written informed consent

• Completed the 48-week study treatment period in the parent study

Exclusion Criteria:

• Subject was permanently discontinued from ARO-APOC3 in the parent study due toelevated glycated hemoglobin (HbA1c), aspartate aminotransferase (AST) or alanineaminotransferase (ALT)

• Any new condition or worsening of existing condition or any other situation thatwould make the subject unsuitable for enrollment, could interfere with the subjectparticipating in or completing the study, would make it difficult to comply withprotocol requirements or put the subject at additional safety risk

• Unwilling to limit alcohol consumption to within moderate limits for the duration ofthe study