The REMIND Study- SPARK Neuro Software Study

Inclusion Criteria:

1. Age 55 to 85 at the time of consent

2. Informant available and willing (remotely or in-person) to provide information aboutsleep patterns and cognitive functioning who spends >8 hours per week with primarysubject

3. Subject or Legally Authorized Representative (LAR) has the ability to provideinformed consent and comply with the protocol.

Exclusion Criteria:

1. Unable to remain still for up to 30 minutes during EEG data recording

2. Subjects currently on and unable to wash out concomitant medications, including: 1)opiates; 2) benzodiazepines and nonbenzodiazepine hypnotics; 3) sedativeantihistamines; 4) tricyclic anti-depressants; 5) skeletal muscle relaxants; 6)antiepileptics; 7) antipsychotics; 8) antimanic agents; 9) THC; 10) anticholinergics

3. Previous history of craniotomy

4. Medical or psychiatric illness that would interfere with study participation

5. History of epilepsy or chronic seizure disorder

6. Presence of non-dental metal in head

7. Currently experiencing a skin disease on scalp that would affect electrode contacts

8. Subject meets at least one of the following criteria:

9. Diagnosis of cognitive impairment from various underlying pathologies asindicated by one of the diagnostic codes listed in Appendix A (protocol)

10. MMSE score of 27 or less

11. Treating physician or PI have documented that the patient is cognitivelyimpaired, with judgment of cognitive impairment having been made within the 6months prior to enrollment

12. Substance Use Disorder, including Alcohol