Phase
Condition
Mood Disorders
Borderline Personality Disorder
Schizotypal Personality Disorder (Spd)
Treatment
Amygdala Neurofeedback
Amygdala Neurofeedback
Clinical Study ID
Ages 18-55 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
right-handed adults (ages 18 - 55) with a primary diagnosis of BorderlinePersonality Disorder according to diagnostic criteria in the Structured Interviewfor DSM Personality Disorders
must be able to give written informed consent prior to participation
unmedicated or stable on an SSRI antidepressant regime (at least 3 weeks to ensuresymptoms are stable)
English speaking
Exclusion
Exclusion Criteria:
have a clinically significant or unstable cardiovascular, pulmonary, endocrine,neurological, gastrointestinal illness or unstable medical disorder
Current moderate or severe DSM-V alcohol or substance use disorder, with theexception of nicotine or caffeine. Clinician will access subjects' alcohol andsubstance use on a case-by-case to determine whether specific cases of mild alcoholor substance use would also interfere with the effects of the intervention.
have a history of traumatic brain injury
are unable to complete MRI scan due to claustrophobia or general MRI exclusions (e.g., shrapnel inside body)
are currently pregnant or breast feeding
are unable to complete questionnaires written in English
current (within 3 weeks of testing) use of any antipsychotics, benzodiazepines,beta-blockers, or other medications (except SSRI antidepressants) likely toinfluence cerebral blood flow. Effective medications will not be discontinued forthe purposes of the study. Inclusion of patients on stable antidepressantmedications was decided in order to allow generalization towards a real worldpopulation
have a DSM-5 diagnosis of psychotic or organic mental disorder
have any eye problems or difficulties in corrected vision.
Serious suidicial ideation
Study Design
Study Description
Connect with a study center
University of Pittsburgh
Pittsburgh, Pennsylvania 15213
United StatesActive - Recruiting
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