Intervention for Monitoring of Salt Intake in Hypertensive Patients

Last updated: June 5, 2022
Sponsor: Mahidol University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Circulation Disorders

Stress

Williams Syndrome

Treatment

N/A

Clinical Study ID

NCT05397054
COA. MURA2021/1004
  • Ages 18-70
  • All Genders

Study Summary

Sodium is an essential nutrient for humans, but excessive sodium consumption is causally associated with high blood pressure and increase risk of cardiovascular diseases. Dietary sodium consumption of greater than the recommended daily amount of 5 grams of salt or 2,000 mg of sodium is a major risk factor for CVD-related mortality. From recent national survey, Thai people had consumed more than 9.1 g of salt per day, which was nearly two times above WHO reference level. Dietary salt reduction was unsuccessful because of lacking awareness, and the higher threshold to detect salt taste in chronic high salt ingestion. To create awareness in the community, we should be educated, managed the environmental for salt reduction, and used salt meter to detect sodium content in daily food. This study aimed to compare the efficacy of intervention; education, reformulation, environmental change and used salt meter compared with standard treatment alone in terms of salt intake reduction and blood pressure.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adults 18-70 years of age with hypertension
  • Systolic blood pressure > 130 mmHg
  • Provided informed consent to participate in the study

Exclusion

Exclusion Criteria:

  • Participants with end stage kidney disease
  • History of adjust antihypertensive agents or diuretic within 2 weeks before enrollment
  • Pregnant or breastfeeding women
  • Adjustment of any antihypertensive agents during study period
  • Participants with salt supplement

Study Design

Total Participants: 240
Study Start date:
January 10, 2022
Estimated Completion Date:
June 30, 2022

Study Description

A randomized-controlled trial was conducted in adult 18-70 years old with hypertensive patients (SBP>130 mmHg) in Uthaithani. Participants were randomized to intervention groups (education, reformulation, environmental change and used salt meter) and control group (standard education and treatment). Trial was followed up for 12 weeks. The primary objective was change in 24-hour urinary sodium excretion between groups and secondary objectives was change in systolic and diastolic blood pressure.

Connect with a study center

  • Faculty of Medicine, Ramathibodi Hospital, Mahidol University

    Bangkok, 10400
    Thailand

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.