Relationship Between Serum N/OFQ and Brain-heart Syndrome

Last updated: February 17, 2023
Sponsor: Zheng Guo
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05344794
hanyi20220418
  • Ages 45-75
  • All Genders

Study Summary

Choosing the neurology patients in the Second Hospital of Shanxi Medical University, diagnosed with patients with cerebral syndrome into the experimental group; patients who did not have cerebral syndrome included in the control group, and all selected people had no intimate relationship with each other.Specimen collecting control group and the study group serum inflammatory factor IL-6, solvent peptide and catecholamine content. The difference between the two groups of data was observed.According to the literature, it is guess: The solitary peptide content of the experimental group will be higher than the control group, and is positively correlated with IL-6, catecholamine content.The difference was statistically significant.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnostic criteria in compliance with cerebral syndrome
  • Acute ischemic stroke patients in line with the "Chinese Acute Ischemic StrokeTreatment Guide 2018" related diagnostic criteria
  • There is no intimate relationship between all selected people and knows this study,and signs informed consent

Exclusion

Exclusion Criteria:

  • Heart-type cerebral infarction, hemorrhagic stroke, brain tumor and past intracranialhemorrhage
  • Complicated with severe cardiovascular complications (such as coronary heart disease,acute coronary syndrome, acute myocardial infarction, chronic heart failure, atrialfibrillation, etc.)
  • Complicated with severe liver and kidney dysfunction (such as coagulous dysfunction,cirrhosis, nephrotic syndrome , Renal failure, etc.)
  • Complicated with severe diabetes complications (such as diabetic nephropathy, diabeticfoot, diabetic acidosis, high blood sugar hypertonic state, diabetes coronary heartdisease, etc.)
  • Complicated with Psychological disease
  • Complicated with chronic obstructive pulmonary disease(COPD)
  • BMI> 40

Study Design

Total Participants: 120
Study Start date:
May 01, 2023
Estimated Completion Date:
October 31, 2023

Connect with a study center

  • Second of Shanxi Medical University

    Taiyuan, Shanxi 030001
    China

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.