Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study

Inclusion Criteria:

• Over 18 years old; children under the age of 18 will be excluded due to rarity ofdisease

• Newly diagnosed with stage I-III breast, colorectal or prostate cancer

• Self-identify as Hispanic or Black

• Are within 4 weeks of initiating chemotherapy

• Overweight or obese (BMI >25kg/m2 or body fat percent >30)

• Physician's clearance to participate in moderate-vigorous intensity exercise

• Speak English or Spanish

• Engaging in less than 90 minutes of moderate-or-vigorous physical activity per week

• Willing to travel to Dana-Farber Cancer Institute for necessary data collection

• Ability to understand and the willingness to sign a written informed consentdocument.

Exclusion Criteria:

• Pre-existing musculoskeletal or cardiorespiratory conditions

• Patients should not have any uncontrolled illness including ongoing or activeinfection, uncontrolled diabetes, hypertension, or thyroid disease

• Patients with other active malignancies

• Patients with metastatic disease

• Participate in more than 90 minutes of structured exercise/week

• Unable to travel to Dana-Farber Cancer Institute for necessary data collection

• Subjects, who in the opinion of the investigator, may not be able to comply with thesafety monitoring requirements of the study.